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    Home > Related Disease > Lupus Nephritis > Lupus Nephritis Basics >

    What is Lupus Nephritis Stage 5

    2014-07-11 07:23| Font Size A A A

    What is Lupus Nephritis Stage 5Lupus Nephritis is kidney inflammation caused by systemic lupus erythematosus (SLE), which is an autoimmune disease--a disorder in which the body’s immune system attacks the body’s own cells and organs. And lupus nephritis is divided into five stages and stage 5 is a advanced stage as well as the end stage.

    What is lupus nephritis stage 5?

    Chronic kidney disease is divided into five stages according to GFR (glomerular filtration rate). And GFR of stage 5 is less than 14%. Healthy people’s GFR can reach 90% to 125%, so the GFR range of stage 5 lupus nephritis is too low.

    It is advanced-stage lupus nephritis and more than 90% global glomerulosclerosis. In such condition, lupus nephritis patients is possible to develop into Kidney Failure or uremia.

    Normally, there are about one million nephrons in our kidney, and patient’s kidney disease will damage these nephrons. As a result, the filtered fluid will reduce, which will cause patients to have low GFR. Stage 4 lupus nephritis means a large amount of nephrons are damaged. And our kidney is in charge of the metabolic balance of electrolyte and acid-base. and kidney can produce urine, and promote the generation of EPO. However, for stage 5 lupus nephritis patients, their damaged kidney almost lose it abilities as they once did.

    What happens in lupus nephritis stage 5?

    In this stage, due to severe damage, patients are prone to experience numerous symptoms and complications during onset of illness.

    --metabolic disorders

    --urine changes like low urine output or anuria.

    --high blood pressure

    --red spot in face

    --blood in urine


    These symptoms has brought much pains and inconvenience to their normal life. It has thought to be life-threatening without effective and timely treatment. In this period, patients have to depend on dialysis to sustain their life, or kidney transplant is available for you.

    All in all, kidney disease can cause many complications to worsen their illness condition, so they should do their best to improve conditions. At our Chronic Kidney Disease (CKD) Treatment Center, we can provide more professional guidance to you. You can leave a message to

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